Web15 jan. 2024 · IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages. Abortive infection of macrophages serves as a … Web8 feb. 2024 · An unstable and rupture-prone plaque is defined by a collagen-poor thin fibrous cap infiltrated by macrophages and lymphocytes with rare or no VSMCs and a relatively large underlying necrotic core. 1 This definition implies that macrophages are over-represented in unstable plaques relative to VSMCs and are considered detrimental …
Single-cell RNA sequencing reveals functional heterogeneity of …
Web1 feb. 2011 · IFIT1 and IFITM3 expression was associated with programmed cell death ligand 1, B7-H4, V-domain Ig suppressor of T-cell activation, indoleamine 2,3 … Webstanding the role of type I IFN and IFITM3 in innate immunity during bacterial infections. Results Type I IFN impairs macrophage killing of phagosome-confined bacteria. To … marylene thiebaut
IFITM6 expression is increased in macrophages of tumor-bearing …
Web15 jan. 2024 · IFITM3 restricts early-stage influenza A virus infection in macrophages. Influenza A virus replication in macrophages is limited by type I interferons. Influenza A … Web16 mrt. 2024 · IFITM3-silenced macrophages infected with Brucella were lysed, and the CFU results showed that compared with the PBS control group, silencing the IFITM3 … WebHost cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs). Although ISGs mediate a protective state against many pathogens, the antiviral functions of the majority of these genes have not been identified. IFITM3 is a small transmembrane ISG that restricts a … husqvarna 240 chainsaw specifications